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CAMK2A/CAMK2D (Phospho-Thr286) Colorimetric Cell-Based ELISA Kit

The CAMK2A/CAMK2D (Phospho-Thr286) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CAMK2A/CAMK2D (Phospho-Thr286) protein expression profile in cells. The kit can be used for measuring the relative amounts of CAMK2A/CAMK2D (Phospho-Thr286) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CAMK2A/CAMK2D (Phospho-Thr286) .

Product Specifications

Synonyms

Calcium/calmodulin-dependent protein kinase type II subunit alpha; CaM kinase II subunit alpha; CaMK-II subunit alpha;2.7.11.17 ; CAMK2A; CAMKA, KIAA0968

Gene Name

CAMK2A

UniProt

Q9UQM7

Reactivity

Human, Mouse, Rat

Applications

ELISA

Detection Range

> 5000 cells/well

Function

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (By similarity) . Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378) . Activates FOXO3 transcriptional activity (By similarity) .

Molecular Weight

54088 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Calcium/calmodulin-dependent protein kinase type II subunit alpha

Subcellular Location

Cell junction, synapse, presynaptic cell membrane.Cell junction, synapse. Postsynaptic lipid rafts.

Frequently Asked Questions

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