BAD (Phospho-Ser112) Colorimetric Cell-Based ELISA Kit

The BAD (Phospho-Ser112) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BAD (Phospho-Ser112) protein expression profile in cells. The kit can be used for measuring the relative amounts of BAD (Phospho-Ser112) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on BAD (Phospho-Ser112) .

Product Specifications

Synonyms

Bcl2-associated agonist of cell death; BAD; Bcl-2-binding component 6; Bcl-2-like protein 8; Bcl2-L-8; Bcl-xL/Bcl-2-associated death promoter; Bcl2 antagonist of cell death; BAD; BBC6, BCL2L8

Gene Name

BAD

UniProt

Q92934

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in a wide variety of tissues.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity) . Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.