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NEK9 (Phospho-Thr210) Colorimetric Cell-Based ELISA Kit

The NEK9 (Phospho-Thr210) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor NEK9 (Phospho-Thr210) protein expression profile in cells. The kit can be used for measuring the relative amounts of NEK9 (Phospho-Thr210) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on NEK9 (Phospho-Thr210) .

Product Specifications

Synonyms

KIAA1995; NERCC; NIMA-related kinase 8; Nek8, Nercc1 kinase; NimA-related protein kinase 9; Serine/threonine-protein kinase Nek9

Gene Name

NEK9

UniProt

Q8TD19

Reactivity

Human, Mouse, Rat

Tissue Specificity

Most abundant in heart, liver, kidney and testis. Also expressed in smooth muscle cells and fibroblasts.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Pleiotropic regulator of mitotic progression, participating in the control of spindle dynamics and chromosome separation. Phosphorylates different histones, myelin basic protein, beta-casein, and BICD2. Phosphorylates histone H3 on serine and threonine residues and beta-casein on serine residues. Important for G1/S transition and S phase progression. Phosphorylates NEK6 and NEK7 and stimulates their activity by releasing the autoinhibitory functions of Tyr-108 and Tyr-97 respectively.

Molecular Weight

107168 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Serine/threonine-protein kinase Nek9

Subcellular Location

Cytoplasm. Nucleus.

Frequently Asked Questions

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