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TOP2A (Phospho-Ser1106) Colorimetric Cell-Based ELISA Kit

The TOP2A (Phospho-Ser1106) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TOP2A (Phospho-Ser1106) protein expression profile in cells. The kit can be used for measuring the relative amounts of TOP2A (Phospho-Ser1106) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TOP2A (Phospho-Ser1106) .

Product Specifications

Synonyms

Alpha isozyme; DNA topoisomerase II; DNA topoisomerase II-alpha; P11388-1; TOP-2; TOP2; TOP2A; TP2A

Gene Name

TOP2A

UniProt

P11388

Reactivity

Human

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation (By similarity) .

Molecular Weight

174385 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

DNA topoisomerase 2-alpha

Subcellular Location

Cytoplasm. Nucleus, nucleoplasm. Generally located in the nucleoplasm.

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