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Histone H1 (Phospho-Thr17) Colorimetric Cell-Based ELISA Kit

The Histone H1 (Phospho-Thr17) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Histone H1 (Phospho-Thr17) protein expression profile in cells. The kit can be used for measuring the relative amounts of Histone H1 (Phospho-Thr17) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Histone H1 (Phospho-Thr17) .

Product Specifications

Synonyms

Histone H1.5; Histone H1a; HIST1H1B; H1F5; Histone H1.3; Histone H1c; HIST1H1D; H1F3; Histone H1.4; Histone H1b; HIST1H1E; H1F4

Gene Name

HIST1H1B

UniProt

P16401

Reactivity

Human, Mouse

Tissue Specificity

Ubiquitous. Expressed in the majority of the cell lines tested and in testis.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation (By similarity) .

Molecular Weight

22580 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Histone H1.5

Subcellular Location

Nucleus. Chromosome. According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin.

Frequently Asked Questions

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