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GRK1 (Phospho-Ser21) Colorimetric Cell-Based ELISA Kit

The GRK1 (Phospho-Ser21) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GRK1 (Phospho-Ser21) protein expression profile in cells. The kit can be used for measuring the relative amounts of GRK1 (Phospho-Ser21) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GRK1 (Phospho-Ser21) .

Product Specifications

Synonyms

RHOK; RK; Rhodopsin kinase; kinase GRK1

Gene Name

GRK1

UniProt

Q15835

Reactivity

Human, Mouse, Rat

Tissue Specificity

Retinal-specific. Expressed in rods and cones cells.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.

Molecular Weight

63526 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Rhodopsin kinase

Subcellular Location

Membrane; Lipid-anchor.

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