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DAPP1 (Phospho-Tyr139) Colorimetric Cell-Based ELISA Kit

The DAPP1 (Phospho-Tyr139) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor DAPP1 (Phospho-Tyr139) protein expression profile in cells. The kit can be used for measuring the relative amounts of DAPP1 (Phospho-Tyr139) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on DAPP1 (Phospho-Tyr139) .

Product Specifications

Synonyms

3' phosphoinositide-interacting SH2 domain containing protein; B lymphocyte adapter protein BAM32; Bam32; Dual adaptor for phosphotyrosine and 3-phosphoinositides 1; PHISH; dual adapter for phosphotyrosine and 3-phosphoinositides

Gene Name

DAPP1

UniProt

Q9UN19

Reactivity

Human, Mouse

Tissue Specificity

Highly expressed in placenta and lung, followed by brain, heart, kidney, liver, pancreas and skeletal muscle. Expressed by B-lymphocytes, but not T-lymphocytes or nonhematopoietic cells.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

May act as a B-cell-associated adapter that regulates B- cell antigen receptor (BCR) -signaling downstream of PI3K.

Molecular Weight

32194 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Dual adapter for phosphotyrosine and 3-phosphotyrosine and 3-phosphoinositide

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein. Membrane-associated after cell stimulation leading to its translocation.

Frequently Asked Questions

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