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CDC25B (Phospho-Ser353) Colorimetric Cell-Based ELISA Kit

The CDC25B (Phospho-Ser353) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CDC25B (Phospho-Ser353) protein expression profile in cells. The kit can be used for measuring the relative amounts of CDC25B (Phospho-Ser353) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CDC25B (Phospho-Ser353) .

Product Specifications

Synonyms

CDC25HU2; CDC25M2; Dual specificity phosphatase Cdc25B; M-phase inducer phosphatase 2; MPIP2

Gene Name

CDC25B

UniProt

P30305

Reactivity

Human

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Directly dephosphorylates CDK1 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

Molecular Weight

64987 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

M-phase inducer phosphatase 2

Subcellular Location

Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole.

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