Calmodulin (Phospho-Thr79+Ser81) Colorimetric Cell-Based ELISA Kit

Calmodulin mediates the control of a large number of enzymes, ion channels, aquaporins and other proteins through calcium-binding. Among the enzymes to be stimulated by the calmodulin-calcium complex are a number of protein kinases and phosphatases. Together with CCP110 and centrin, is involved in a genetic pathway that regulates the centrosome cycle and progression through cytokinesis (PubMed:16760425) . Mediates calcium-dependent inactivation of CACNA1C (PubMed:26969752) . Positively regulates calcium-activated potassium channel activity of KCNN2 (PubMed:27165696) .

Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Distributed throughout the cell during interphase, but during mitosis becomes dramatically localized to the spindle poles and the spindle microtubules.