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BAD (Phospho-Ser134) Colorimetric Cell-Based ELISA Kit

The BAD (Phospho-Ser134) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BAD (Phospho-Ser134) protein expression profile in cells. The kit can be used for measuring the relative amounts of BAD (Phospho-Ser134) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on BAD (Phospho-Ser134) .

Product Specifications

Synonyms

BAD; BBC6; Bcl- XL/Bcl-2 associated death promoter; Bcl-2 binding component 6; Bcl-2-like 8 protein; Bcl-xL/Bcl-2 associated death promoter; Bcl2-antagonist of cell death; BCL2L8

Gene Name

BAD

UniProt

Q92934

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in a wide variety of tissues.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Promotes cell death. Successfully competes for the binding to Bcl-X (L), Bcl-2 and Bcl-W, thereby affecting the level of heterodimerization of these proteins with BAX. Can reverse the death repressor activity of Bcl-X (L), but not that of Bcl-2 (By similarity) . Appears to act as a link between growth factor receptor signaling and the apoptotic pathways.

Molecular Weight

18392 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC2216

Product MSDS

https://www.bosterbio.com/msds?sku=EKC2216

Other Gene Names

Bcl2-associated agonist of cell death

Subcellular Location

Mitochondrion outer membrane. Cytoplasm. Colocalizes with HIF3A in the cytoplasm (By similarity) . Upon phosphorylation, locates to the cytoplasm.

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