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ALOX5 (Phospho-Ser271) Colorimetric Cell-Based ELISA Kit

The ALOX5 (Phospho-Ser271) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ALOX5 (Phospho-Ser271) protein expression profile in cells. The kit can be used for measuring the relative amounts of ALOX5 (Phospho-Ser271) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ALOX5 (Phospho-Ser271) .

Product Specifications

Synonyms

5-lipoxygenase; ALOX5; Arachidonate 5-lipoxygenase; LOG5; LOX5

Gene Name

ALOX5

UniProt

P09917

Reactivity

Human, Mouse, Rat

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Catalyzes the first step in leukotriene biosynthesis, and thereby plays a role in inflammatory processes.

Molecular Weight

77983 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Arachidonate 5-lipoxygenase

Subcellular Location

Cytoplasm. Nucleus matrix. Nucleus membrane; Peripheral membrane protein. Shuttles between cytoplasm and nucleus. Found exclusively in the nucleus, when phosphorylated on Ser-272. Calcium binding promotes translocation from the cytosol and the nuclear matrix to the nuclear envelope and membrane association.

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