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14-3-3 theta/tau (Phospho-Ser232) Colorimetric Cell-Based ELISA Kit

The 14-3-3 theta/tau (Phospho-Ser232) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor 14-3-3 theta/tau (Phospho-Ser232) protein expression profile in cells. The kit can be used for measuring the relative amounts of 14-3-3 theta/tau (Phospho-Ser232) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on 14-3-3 theta/tau (Phospho-Ser232) .

Product Specifications

Synonyms

14-3-3 protein T-cell;14-3-3 protein tau;1433T;143T; HS1 protein; YWHAQ

Gene Name

YWHAQ

UniProt

P27348

Reactivity

Human, Mouse, Rat

Tissue Specificity

Abundantly expressed in brain, heart and pancreas, and at lower levels in kidney and placenta. Up-regulated in the lumbar spinal cord from patients with sporadic amyotrophic lateral sclerosis (ALS) compared with controls, with highest levels of expression in individuals with predominant lower motor neuron involvement.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. Negatively regulates the kinase activity of PDPK1.

Molecular Weight

27764 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

14-3-3 protein theta

Subcellular Location

Cytoplasm. In neurons, axonally transported to the nerve terminals.

Frequently Asked Questions

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