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PBK/TOPK (Phospho-Thr9) Colorimetric Cell-Based ELISA Kit

The PBK/TOPK (Phospho-Thr9) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor PBK/TOPK (Phospho-Thr9) protein expression profile in cells. The kit can be used for measuring the relative amounts of PBK/TOPK (Phospho-Thr9) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on PBK/TOPK (Phospho-Thr9) .

Product Specifications

Synonyms

MPAKK-like protein kinase cap site form 2; NORI-3; TOPK

Gene Name

PBK

UniProt

Q96KB5

Reactivity

Human

Tissue Specificity

Expressed in the testis and placenta. In the testis, restrictedly expressed in outer cell layer of seminiferous tubules.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Phosphorylates MAP kinase p38. Seems to be active only in mitosis. May also play a role in the activation of lymphoid cells. When phosphorylated, forms a complex with TP53, leading to TP53 destabilization and attenuation of G2/M checkpoint during doxorubicin-induced DNA damage.

Molecular Weight

36085 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Lymphokine-activated killer T-cell-originated protein kinase

Frequently Asked Questions

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