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BCAR1 (Phospho-Tyr249) Colorimetric Cell-Based ELISA Kit

The BCAR1 (Phospho-Tyr249) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor BCAR1 (Phospho-Tyr249) protein expression profile in cells. The kit can be used for measuring the relative amounts of BCAR1 (Phospho-Tyr249) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on BCAR1 (Phospho-Tyr249) .

Product Specifications

Synonyms

BCA1; BCAR1; Breast cancer anti-estrogen resistance 1 protein; CAS; CRK-associated substrate; CRKAS

Gene Name

BCAR1

UniProt

P56945

Reactivity

Human, Mouse, Rat

Tissue Specificity

Widely expressed with an abundant expression in the testis. Low level of expression seen in the liver, thymus, and peripheral blood leukocytes. The protein has been detected in a B-cell line.

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Docking protein which plays a central coordinating role for tyrosine kinase-based signaling related to cell adhesion. Implicated in induction of cell migration. Overexpression confers antiestrogen resistance on breast cancer cells.

Molecular Weight

93372 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Breast cancer anti-estrogen resistance protein 1

Subcellular Location

Cell junction, focal adhesion. Cytoplasm. Unphosphorylated form localizes in the cytoplasm and can move to the membrane upon tyrosine phosphorylation.

Frequently Asked Questions

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