TEBP (Phospho-Ser113) Colorimetric Cell-Based ELISA Kit
The TEBP (Phospho-Ser113) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TEBP (Phospho-Ser113) protein expression profile in cells. The kit can be used for measuring the relative amounts of TEBP (Phospho-Ser113) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TEBP (Phospho-Ser113) .
Product Specifications
Synonyms
Prostaglandin E synthase 3; Cytosolic prostaglandin E2 synthase; cPGES; Telomerase-binding protein p23; Hsp90 co-chaperone; Progesterone receptor complex p23; PTGES3P23; TEBP
Gene Name
PTGES3
UniProt
Q15185
Reactivity
Human, Mouse, Rat
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363) . Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419) . Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway (PubMed:24711448) .
Molecular Weight
18697 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Prostaglandin E synthase 3
Subcellular Location
Cytoplasm.
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