GRK2 (Phospho-Ser29) Colorimetric Cell-Based ELISA Kit
The GRK2 (Phospho-Ser29) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor GRK2 (Phospho-Ser29) protein expression profile in cells. The kit can be used for measuring the relative amounts of GRK2 (Phospho-Ser29) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on GRK2 (Phospho-Ser29) .
Product Specifications
Synonyms
ADRBK1; ARBK1; BARK; BARK1; beta-adrenergic receptor kinase 1; beta-ARK-1; G protein receptor kinase 2; G- protein coupled receptor kinase 2; kinase GRK2
Gene Name
GRK2
UniProt
P25098
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed in peripheral blood leukocytes.
Applications
ELISA
Sample Type
Cell lines
Detection Range
> 5000 cells/well
Function
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner.
Molecular Weight
79574 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Beta-adrenergic receptor kinase 1
Subcellular Location
Cytoplasm. Cell membrane.
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