CREB (Phospho-Ser121) Colorimetric Cell-Based ELISA Kit

The CREB (Phospho-Ser121) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CREB (Phospho-Ser121) protein expression profile in cells. The kit can be used for measuring the relative amounts of CREB (Phospho-Ser121) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CREB (Phospho-Ser121) .

Product Specifications

Synonyms

CAMP responsive element binding protein 1; cAMP-response element binding protein; CREB-1; CREB1

Gene Name

CREB1

UniProt

P16220

Reactivity

Human, Mouse, Rat

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells.