H3 (Phospho-Ser28) ColorHistone imetric Cell-Based ELISA Kit

The H3 (Phospho-Ser28) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor H3 (Phospho-Ser28) protein expression profile in cells. The kit can be used for measuring the relative amounts of H3 (Phospho-Ser28) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on H3 (Phospho-Ser28) .

Product Specifications

Synonyms

H3/a; H3/c; H3/d; H3/f; H3/h; H3/i; H3/j; H3/k; H3/l; H31; HIST1H3A; histone H3.1

Gene Name

HIST1H3AHIST1H3BHIST1H3CHIST1H3DHIST1H3EHIST1H3FHIST1H3GHIST1H3HHIST1H3IHIST1H3J

UniProt

P68431

Reactivity

Human, Mouse, Rat

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.