PLCG1 (Phospho-Tyr783) Colorimetric Cell-Based ELISA Kit

The PLCG1 (Phospho-Tyr783) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor PLCG1 (Phospho-Tyr783) protein expression profile in cells. The kit can be used for measuring the relative amounts of PLCG1 (Phospho-Tyr783) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on PLCG1 (Phospho-Tyr783) .

Product Specifications

Synonyms

1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1; PLCG1; PLC1

Gene Name

PLCG1

UniProt

P19174

Reactivity

Human, Mouse, Rat

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . Plays an important role in the regulation of intracellular signaling cascades. Becomes activated in response to ligand- mediated activation of receptor-type tyrosine kinases, such as PDGFRA, PDGFRB, FGFR1, FGFR2, FGFR3 and FGFR4. Plays a role in actin reorganization and cell migration.

Molecular Weight

148532 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1994

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1994

Other Gene Names

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

Subcellular Location

Cell projection, lamellipodium. Cell projection, ruffle. Rapidly redistributed to ruffles and lamellipodia structures in response to epidermal growth factor (EGF) treatment.