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KSR (Phospho-Ser392) Colorimetric Cell-Based ELISA Kit

The KSR (Phospho-Ser392) Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor KSR (Phospho-Ser392) protein expression profile in cells. The kit can be used for measuring the relative amounts of KSR (Phospho-Ser392) in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on KSR (Phospho-Ser392) .

Product Specifications

Synonyms

CAP kinase; HB; HB protein; Kinase suppressor of RAS-1; ceramide-activated protein kinase; kinase KSR1

Gene Name

KSR1

UniProt

Q8IVT5

Reactivity

Human, Mouse

Applications

ELISA

Sample Type

Cell lines

Detection Range

> 5000 cells/well

Function

Scaffolding protein that is part of a multiprotein signaling complex. Promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Does not have kinase activity by itself.

Molecular Weight

102160 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1989

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1989

Other Gene Names

Kinase suppressor of Ras 1

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein. Cell membrane; Peripheral membrane protein. Cell projection, ruffle membrane. Endoplasmic reticulum membrane. In unstimulated cells, where the phosphorylated form is bound to a 14-3-3 protein, sequestration in the cytoplasm occurs. Following growth factor treatment, the protein is free for membrane translocation, and it moves from the cytoplasm to the cell periphery.
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