Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

AFX Colorimetric Cell-Based ELISA

The AFX Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor AFX protein expression profile in cells. The kit can be used for measuring the relative amounts of AFX in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on AFX.

Product Specifications

Synonyms

Forkhead box protein O4; Fork head domain transcription factor AFX1; FOXO4; AFX, AFX1, MLLT7

Gene Name

FOXO4

UniProt

P98177

Reactivity

Human, Mouse

Tissue Specificity

Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Isoform zeta is most abundant in the liver, kidney, and pancreas.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. Down-regulates expression of HIF1A and suppresses hypoxia-induced transcriptional activation of HIF1A-modulated genes. Also involved in negative regulation of the cell cycle. Involved in increased proteasome activity in embryonic stem cells (ESCs) by activating expression of PSMD11 in ESCs, leading to enhanced assembly of the 26S proteasome, followed by higher proteasome activity.

Molecular Weight

53684 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Forkhead box protein O4

Subcellular Location

Cytoplasm. Nucleus. When phosphorylated, translocated from nucleus to cytoplasm. Dephosphorylation triggers nuclear translocation. Monoubiquitination increases nuclear localization. When deubiquitinated, translocated from nucleus to cytoplasm.

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Rabbit Polyclonal NAC1 Antibody [mFluor Violet 450 SE]
NBP2-99428MFV450 0.1 mL

Rabbit Polyclonal NAC1 Antibody [mFluor Violet 450 SE]

Sign In for Pricing
View Details
Anti-NCKAP1 Antibody Picoband® Fluoro647 Conjugated
A09238-1-Fluoro647 100 µg/Vial

Anti-NCKAP1 Antibody Picoband® Fluoro647 Conjugated

Sign In for Pricing
View Details
CAPNS1 Protein Vector (Human) (pPB-C-His)
PV007457 500 ng

CAPNS1 Protein Vector (Human) (pPB-C-His)

Sign In for Pricing
View Details
Glycerol kinase pseudogene 3
317534 100 µL

Glycerol kinase pseudogene 3

Sign In for Pricing
View Details
N-L-Tartaryl Linagliptin
TRC-T007675-100MG 100 mg

N-L-Tartaryl Linagliptin

Sign In for Pricing
View Details
Recombinant Human PTH1-84, 15N
P6965-10μg 10 µg

Recombinant Human PTH1-84, 15N

Sign In for Pricing
View Details