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ADRB2 Colorimetric Cell-Based ELISA

The ADRB2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ADRB2 protein expression profile in cells. The kit can be used for measuring the relative amounts of ADRB2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ADRB2.

Product Specifications

Synonyms

Beta-2 adrenergic receptor; Beta-2 adrenoreceptor; Beta-2 adrenoceptor; ADRB2; ADRB2R, B2AR

Gene Name

ADRB2

UniProt

P07550

Reactivity

Human, Mouse, Rat

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Beta-adrenergic receptors mediate the catecholamine- induced activation of adenylate cyclase through the action of G proteins. The beta-2-adrenergic receptor binds epinephrine with an approximately 30-fold greater affinity than it does norepinephrine.

Molecular Weight

46459 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Beta-2 adrenergic receptor

Subcellular Location

Cell membrane; Multi- pass membrane protein. Early endosome. Colocalizes with VHL at the cell membrane (PubMed:19584355) . Activated receptors are internalized into endosomes prior to their degradation in lysosomes (PubMed:20559325) .

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