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Cytochrome P450 26A1 Colorimetric Cell-Based ELISA

The Cytochrome P450 26A1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Cytochrome P450 26A1 protein expression profile in cells. The kit can be used for measuring the relative amounts of Cytochrome P450 26A1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Cytochrome P450 26A1.

Product Specifications

Synonyms

Cytochrome P450 26A1;1.14.13.- ; Cytochrome P450 retinoic acid-inactivating 1; Cytochrome P450RAI; hP450RAI; Retinoic acid 4-hydroxylase; Retinoic acid-metabolizing cytochrome; CYP26A1; CYP26, P450RAI1

Gene Name

CYP26A1

UniProt

O43174

Reactivity

Human, Mouse, Rat

Tissue Specificity

Highest levels in adult liver, heart, pituitary gland, adrenal gland, placenta and regions of the brain.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Plays a key role in retinoic acid metabolism. Acts on retinoids, including all-trans-retinoic acid (RA) and its stereoisomer 9-cis-RA. Capable of both 4-hydroxylation and 18- hydroxylation. Responsible for generation of several hydroxylated forms of RA, including 4-OH-RA, 4-oxo-RA and 18-OH-RA.

Molecular Weight

56199 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Cytochrome P450 26A1

Subcellular Location

Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.

Frequently Asked Questions

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