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Cytochrome P450 24A1 Colorimetric Cell-Based ELISA

The Cytochrome P450 24A1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Cytochrome P450 24A1 protein expression profile in cells. The kit can be used for measuring the relative amounts of Cytochrome P450 24A1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Cytochrome P450 24A1.

Product Specifications

Synonyms

1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial;24-OHase; Vitamin D (3) 24-hydroxylase;1.14.15.16 ; Cytochrome P450 24A1; Cytochrome P450-CC24; CYP24A1; CYP24

Gene Name

CYP24A1

UniProt

Q07973

Reactivity

Human

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Has a role in maintaining calcium homeostasis. Catalyzes the adrenodoxin-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D (3) ) and calcitriol (1-alpha,25-dihydroxyvitamin D (3) ) . The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D (3) -26,23-lactone as end product.

Molecular Weight

58875 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1907

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1907

Other Gene Names

1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial

Subcellular Location

Mitochondrion.

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