Cytochrome P450 24A1 Colorimetric Cell-Based ELISA
The Cytochrome P450 24A1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Cytochrome P450 24A1 protein expression profile in cells. The kit can be used for measuring the relative amounts of Cytochrome P450 24A1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Cytochrome P450 24A1.
Product Specifications
Synonyms
1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial;24-OHase; Vitamin D (3) 24-hydroxylase;1.14.15.16 ; Cytochrome P450 24A1; Cytochrome P450-CC24; CYP24A1; CYP24
Gene Name
CYP24A1
UniProt
Q07973
Reactivity
Human
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Has a role in maintaining calcium homeostasis. Catalyzes the adrenodoxin-dependent 24-hydroxylation of calcidiol (25- hydroxyvitamin D (3) ) and calcitriol (1-alpha,25-dihydroxyvitamin D (3) ) . The enzyme can perform up to 6 rounds of hydroxylation of calcitriol leading to calcitroic acid. It also shows 23- hydroxylating activity leading to 1-alpha,25-dihydroxyvitamin D (3) -26,23-lactone as end product.
Molecular Weight
58875 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
1,25-dihydroxyvitamin D (3) 24-hydroxylase, mitochondrial
Subcellular Location
Mitochondrion.
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