Cytochrome P450 17A1 Colorimetric Cell-Based ELISA
The Cytochrome P450 17A1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Cytochrome P450 17A1 protein expression profile in cells. The kit can be used for measuring the relative amounts of Cytochrome P450 17A1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Cytochrome P450 17A1.
Product Specifications
Synonyms
Steroid 17-alpha-hydroxylase/17,20 lyase;1.14.14.19 ;17-alpha-hydroxyprogesterone aldolase;1.14.14.32 ; CYPXVII; Cytochrome P450 17A1; Cytochrome P450-C17; Cytochrome P450c17; Steroid 17-alpha-monooxygenase; CYP17A1; CYP17, S17AH
Gene Name
CYP17A1
UniProt
P05093
Reactivity
Human
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Conversion of pregnenolone and progesterone to their 17- alpha-hydroxylated products and subsequently to dehydroepiandrosterone (DHEA) and androstenedione. Catalyzes both the 17-alpha-hydroxylation and the 17,20-lyase reaction. Involved in sexual development during fetal life and at puberty.
Molecular Weight
57371 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Steroid 17-alpha-hydroxylase/17,20 lyase
Subcellular Location
Membrane.
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