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ADCK4 Colorimetric Cell-Based ELISA

The ADCK4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ADCK4 protein expression profile in cells. The kit can be used for measuring the relative amounts of ADCK4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ADCK4.

Product Specifications

Synonyms

Atypical kinase COQ8B, mitochondrial ;2.7.-.- ; AarF domain-containing protein kinase 4 ; Coenzyme Q protein 8B ; COQ8B ; ADCK4

Gene Name

COQ8B ADCK4

UniProt

Q96D53

Reactivity

Human, Mouse, Rat

Tissue Specificity

Widely expressed, including renal podocytes.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:24270420) . Its substrate specificity is unclear: does not show any protein kinase activity. Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway. Required for podocyte migration (PubMed:24270420) .

Molecular Weight

60069 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Atypical kinase COQ8B, mitochondrial

Subcellular Location

Mitochondrion membrane; Single-pass membrane protein. Cytoplasm, cytosol. Cell membrane.

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