DCLK2 Colorimetric Cell-Based ELISA

The DCLK2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor DCLK2 protein expression profile in cells. The kit can be used for measuring the relative amounts of DCLK2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on DCLK2.

Product Specifications

Synonyms

Serine/threonine-protein kinase DCLK2;2.7.11.1; CaMK-like CREB regulatory kinase 2; CL2; CLICK-II; CLICK2; Doublecortin domain-containing protein 3B; Doublecortin-like and CAM kinase-like 2; Doublecortin-like kinase 2; DCLK2; DCAMKL2, DCDC3B, DCK2

Gene Name

DCLK2

UniProt

Q8N568

Reactivity

Human, Mouse

Tissue Specificity

Expressed in the brain, heart and eyes.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Protein kinase with a significantly reduced C (a2+) /CAM affinity and dependence compared to other members of the CaMK family. May play a role in the down-regulation of CRE-dependent gene activation probably by phosphorylation of the CREB coactivator CRTC2/TORC2 and the resulting retention of TORC2 in the cytoplasm (By similarity) .