CCRK Colorimetric Cell-Based ELISA
The CCRK Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CCRK protein expression profile in cells. The kit can be used for measuring the relative amounts of CCRK in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CCRK.
Product Specifications
Synonyms
Cyclin-dependent kinase 20;2.7.11.22; CDK-activating kinase p42; CAK-kinase p42; Cell cycle-related kinase; Cell division protein kinase 20; Cyclin-dependent protein kinase H; Cyclin-kinase-activating kinase p42; CDK20; CCRK, CDCH
Gene Name
CDK20
UniProt
Q8IZL9
Reactivity
Human, Mouse, Rat
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity) . Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
Molecular Weight
38695 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Cyclin-dependent kinase 20
Subcellular Location
Nucleus. Cytoplasm. Cell projection, cilium.
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