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CERKL Colorimetric Cell-Based ELISA

The CERKL Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CERKL protein expression profile in cells. The kit can be used for measuring the relative amounts of CERKL in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CERKL.

Product Specifications

Synonyms

Ceramide kinase-like protein; CERKL

Gene Name

CERKL

UniProt

Q49MI3

Reactivity

Human

Tissue Specificity

Isoform 1 and isoform 2 are expressed in adult retina, liver and pancreas as well as in fetal brain, lung and kidney. Isoform 3 is expressed in adult retina as well as in fetal lung and liver. Isoform 4 is expressed in adult retina, lung and kidney as well as in fetal lung and liver. Moderately expressed in retina, kidney, lung, testis, trachea, and pancreas. Weakly expressed in brain, placenta and liver.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Has no detectable ceramide-kinase activity. Overexpression of CERKL protects cells from apoptosis in oxidative stress conditions.

Molecular Weight

62622 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Ceramide kinase-like protein

Subcellular Location

Cytoplasm. Nucleus, nucleolus. Enriched in nucleoli. May shuttle between nucleus and cytoplasm. Isoform 5 is not enriched in the nucleoli.

Frequently Asked Questions

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