Smad1/5/9 Colorimetric Cell-Based ELISA
The Smad1/5/9 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor Smad1/5/9 protein expression profile in cells. The kit can be used for measuring the relative amounts of Smad1/5/9 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on Smad1/5/9.
Product Specifications
Synonyms
Mothers against decapentaplegic homolog 1; MAD homolog 1; Mothers against DPP homolog 1; JV4-1; Mad-related protein 1; SMAD family member 1; SMAD 1; Smad1; hSMAD1; Transforming growth factor-beta-signaling protein 1; BSP-1; SMAD1; BSP1, MADH1, MADR1
Gene Name
SMAD1
UniProt
Q15797
Reactivity
Human, Mouse, Rat
Tissue Specificity
Ubiquitous. Highest expression seen in the heart and skeletal muscle.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD) . SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP) -mediated cardiac-specific gene expression.
Molecular Weight
52260 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Mothers against decapentaplegic homolog 1
Subcellular Location
Cytoplasm. Nucleus. Cytoplasmic in the absence of ligand. Migrates to the nucleus when complexed with SMAD4 (PubMed:15647271) . Co-localizes with LEMD3 at the nucleus inner membrane (PubMed:15647271) . Exported from the nucleus to the cytoplasm when dephosphorylated (By similarity) .
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
BNC400270-100 1x 100 µL
Fibronectin (HFN7.1), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC680204-100 1x 100 µL
Complement C4d (C4D204), CF568 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 