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OGR-1 Colorimetric Cell-Based ELISA

The OGR-1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor OGR-1 protein expression profile in cells. The kit can be used for measuring the relative amounts of OGR-1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on OGR-1.

Product Specifications

Synonyms

Ovarian cancer G-protein coupled receptor 1; OGR-1; G-protein coupled receptor 68; GPR12A; Sphingosylphosphorylcholine receptor; GPR68; OGR1

Gene Name

GPR68

UniProt

Q15743

Reactivity

Human, Mouse

Tissue Specificity

Found at low level in a wide range of tissues, but significantly expressed in lung, kidney, bone and nervous system.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca (2+) mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer (By similarity) .

Molecular Weight

41077 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Ovarian cancer G-protein coupled receptor 1

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Frequently Asked Questions

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