NR1I3 Colorimetric Cell-Based ELISA
The NR1I3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor NR1I3 protein expression profile in cells. The kit can be used for measuring the relative amounts of NR1I3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on NR1I3.
Product Specifications
Synonyms
Nuclear receptor subfamily 1 group I member 3; Constitutive activator of retinoid response; Constitutive active response; Constitutive androstane receptor; CAR; Orphan nuclear receptor MB67; NR1I3; CAR
Gene Name
NR1I3
UniProt
Q14994
Reactivity
Human
Tissue Specificity
Predominantly expressed in liver.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Binds and transactivates the retinoic acid response elements that control expression of the retinoic acid receptor beta 2 and alcohol dehydrogenase 3 genes. Transactivates both the phenobarbital responsive element module of the human CYP2B6 gene and the CYP3A4 xenobiotic response element.
Molecular Weight
39942 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Nuclear receptor subfamily 1 group I member 3
Subcellular Location
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Recruited to the cytoplasm by DNAJC7.
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