FOXE3 Colorimetric Cell-Based ELISA
The FOXE3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor FOXE3 protein expression profile in cells. The kit can be used for measuring the relative amounts of FOXE3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on FOXE3.
Product Specifications
Synonyms
Forkhead box protein E3; Forkhead-related protein FKHL12; Forkhead-related transcription factor 8; FREAC-8; FOXE3; FKHL12, FREAC8
Gene Name
FOXE3
UniProt
Q13461
Reactivity
Human, Mouse, Rat
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Transcription factor that controls lens epithelial cell growth through regulation of proliferation, apoptosis and cell cycle (PubMed:22527307, PubMed:25504734) . During lens development, controls the ratio of the lens fiber cells to the cells of the anterior lens epithelium by regulating the rate of proliferation and differentiation (By similarity) . Controls lens vesicle closure and subsequent separation of the lens vesicle from ectoderm (By similarity) . Controls the expression of DNAJB1 in a pathway that is crucial for the development of the anterior segment of the eye (PubMed:27218149) .
Molecular Weight
33234 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Forkhead box protein E3
Subcellular Location
Nucleus.
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