TLE4 Colorimetric Cell-Based ELISA
The TLE4 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TLE4 protein expression profile in cells. The kit can be used for measuring the relative amounts of TLE4 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TLE4.
Product Specifications
Synonyms
Transducin-like enhancer protein 4; Grg-4; Groucho-related protein 4; TLE4; GRG4, KIAA1261
Gene Name
TLE4
UniProt
Q04727
Reactivity
Human, Mouse, Rat
Tissue Specificity
In all tissues examined, mostly in brain, and muscle.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Essential for the transcriptional repressor activity of SIX3 during retina and lens development and for SIX3 transcriptional auto-repression (By similarity) .
Molecular Weight
83755 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Transducin-like enhancer protein 4
Subcellular Location
Nucleus.
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