CREM Colorimetric Cell-Based ELISA
The CREM Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CREM protein expression profile in cells. The kit can be used for measuring the relative amounts of CREM in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CREM.
Product Specifications
Synonyms
CAMP-responsive element modulator; Inducible cAMP early repressor; ICER; CREM
Gene Name
CREM
UniProt
Q03060
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed in testes (round spermatids) (at protein level) . Isoform 14 is the major activator form in testes.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Transcriptional regulator that binds the cAMP response element (CRE), a sequence present in many viral and cellular promoters. Isoforms are either transcriptional activators or repressors. Plays a role in spermatogenesis and is involved in spermatid maturation (PubMed:10373550) .
Molecular Weight
38940 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
CAMP-responsive element modulator
Subcellular Location
Nucleus.
Frequently Asked Questions
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