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FOXK1 Colorimetric Cell-Based ELISA

The FOXK1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor FOXK1 protein expression profile in cells. The kit can be used for measuring the relative amounts of FOXK1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on FOXK1.

Product Specifications

Synonyms

Forkhead box protein K1; Myocyte nuclear factor; MNF; FOXK1 ; MNF

Gene Name

FOXK1 MNF

UniProt

P85037

Reactivity

Human, Mouse

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Transcriptional regulator that binds to the upstream enhancer region (CCAC box) of myoglobin gene (By similarity) . Important regulatory factor of the myogenic progenitor cell population (By similarity) . Involved in the cell cycle process, promotes proliferation by repressing Foxo4 transcriptional activity and the cyclin-dependent kinase inhibitor, p21CIP, in the myogenic progenitor cells (By similarity) . Represses myogenic differentiation by inhibiting MEFC acitivity (By similarity) . Has a role in remodeling processes of adult muscles that occur in response to physiological stimuli (By similarity) . Required to correct temporal orchestration of molecular and cellular events necessary for muscle repair (By similarity) . Positively regulates Wnt/beta-catenin signaling by translocating DVL into the nucleus (PubMed:25805136) . Reduces virus replication, probably by binding the interferon stimulated response element (ISRE) to promote antiviral gene expression (PubMed:25852164) .

Molecular Weight

75457 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Forkhead box protein K1

Subcellular Location

Nucleus. Cytoplasm. (Microbial infection) Accumulates in the nucleus upon viral infection.

Frequently Asked Questions

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