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TMPRSS3 Colorimetric Cell-Based ELISA

The TMPRSS3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor TMPRSS3 protein expression profile in cells. The kit can be used for measuring the relative amounts of TMPRSS3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on TMPRSS3.

Product Specifications

Synonyms

Transmembrane protease serine 3;3.4.21.-; Serine protease TADG-12; Tumor-associated differentially-expressed gene 12 protein; TMPRSS3; ECHOS1, TADG12; UNQ323/PRO382

Gene Name

TMPRSS3

UniProt

P57727

Reactivity

Human, Mouse

Tissue Specificity

Expressed in many tissues including fetal cochlea. Isoform T is found at increased levels in some carcinomas.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Probable serine protease that plays a role in hearing. Acts as a permissive factor for cochlear hair cell survival and activation at the onset of hearing and is required for saccular hair cell survival (By similarity) . Activates ENaC (in vitro) .

Molecular Weight

49405 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Transmembrane protease serine 3

Subcellular Location

Endoplasmic reticulum membrane; Single-pass type II membrane protein.

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