EFNA3 Colorimetric Cell-Based ELISA

The EFNA3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor EFNA3 protein expression profile in cells. The kit can be used for measuring the relative amounts of EFNA3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on EFNA3.

Product Specifications

Synonyms

Ephrin-A3; EFL-2; EHK1 ligand; EHK1-L; EPH-related receptor tyrosine kinase ligand 3; LERK-3; EFNA3; EFL2, EPLG3, LERK3

Gene Name

EFNA3

UniProt

P52797

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in brain, skeletal muscle, spleen, thymus, prostate, testis, ovary, small intestine, and peripheral blood leukocytes.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Cell surface GPI-bound ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity) .