MEOX2 Colorimetric Cell-Based ELISA
The MEOX2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MEOX2 protein expression profile in cells. The kit can be used for measuring the relative amounts of MEOX2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MEOX2.
Product Specifications
Synonyms
Homeobox protein MOX-2; Growth arrest-specific homeobox; Mesenchyme homeobox 2; MEOX2; GAX, MOX2
Gene Name
MEOX2
UniProt
P50222
Reactivity
Human, Mouse, Rat
Tissue Specificity
Embryo and placenta.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Mesodermal transcription factor that plays a key role in somitogenesis and is required for sclerotome development (By similarity) . Activates expression of CDKN1A and CDKN2A in endothelial cells, acting as a regulator of vascular cell proliferation. While it activates CDKN1A in a DNA-dependent manner, it activates CDKN2A in a DNA-independent manner (PubMed:22206000) . May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.
Molecular Weight
33594 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Homeobox protein MOX-2
Subcellular Location
Nucleus. Nucleus speckle.
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