ERCC5 Colorimetric Cell-Based ELISA
The ERCC5 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor ERCC5 protein expression profile in cells. The kit can be used for measuring the relative amounts of ERCC5 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on ERCC5.
Product Specifications
Synonyms
DNA repair protein complementing XP-G cells;3.1.-.-; DNA excision repair protein ERCC-5; Xeroderma pigmentosum group G-complementing protein; ERCC5; ERCM2, XPG, XPGC
Gene Name
ERCC5
UniProt
P28715
Reactivity
Human
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER) . Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too.
Molecular Weight
133108 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
DNA repair protein complementing XP-G cells
Subcellular Location
Nucleus.
Frequently Asked Questions
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