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AKAP5 Colorimetric Cell-Based ELISA

The AKAP5 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor AKAP5 protein expression profile in cells. The kit can be used for measuring the relative amounts of AKAP5 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on AKAP5.

Product Specifications

Synonyms

A-kinase anchor protein 5; AKAP-5; A-kinase anchor protein 79 kDa; AKAP 79; H21; cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein; AKAP5; AKAP79

Gene Name

AKAP5

UniProt

P24588

Reactivity

Human

Tissue Specificity

Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

May anchor the PKA protein to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors. Association with to the beta2-adrenergic receptor (beta2-AR) not only regulates beta2-AR signaling pathway, but also the activation by PKA by switching off the beta2-AR signaling cascade.

Molecular Weight

47088 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1695

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1695

Other Gene Names

A-kinase anchor protein 5

Subcellular Location

Membrane; Lipid-anchor. Associates with lipid rafts.

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