IRF2 Colorimetric Cell-Based ELISA
The IRF2 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor IRF2 protein expression profile in cells. The kit can be used for measuring the relative amounts of IRF2 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on IRF2.
Product Specifications
Synonyms
Interferon regulatory factor 2; IRF-2; IRF2
Gene Name
IRF2
UniProt
P14316
Reactivity
Human, Mouse, Rat
Tissue Specificity
Expressed throughout the epithelium of the colon. Also expressed in lamina propria.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS) ) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.
Molecular Weight
39354 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Interferon regulatory factor 2
Subcellular Location
Nucleus.
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