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MBD3 Colorimetric Cell-Based ELISA

The MBD3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor MBD3 protein expression profile in cells. The kit can be used for measuring the relative amounts of MBD3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on MBD3.

Product Specifications

Synonyms

Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3; MBD3

Gene Name

MBD3

UniProt

O95983

Reactivity

Human, Mouse

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Acts as transcriptional repressor and plays a role in gene silencing. Does not bind to DNA by itself (PubMed:12124384) . Binds to DNA with a preference for sites containing methylated CpG dinucleotides (in vitro) . Binds to a lesser degree DNA containing unmethylated CpG dinucleotides (PubMed:24307175) . Recruits histone deacetylases and DNA methyltransferases.

Molecular Weight

32844 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=EKC1665

Product MSDS

https://www.bosterbio.com/msds?sku=EKC1665

Other Gene Names

Methyl-CpG-binding domain protein 3

Subcellular Location

Nucleus. Chromosome. Nuclear, in discrete foci. Detected on chromatin, at promoter regions of active genes.

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