CBX6 Colorimetric Cell-Based ELISA
The CBX6 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor CBX6 protein expression profile in cells. The kit can be used for measuring the relative amounts of CBX6 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on CBX6.
Product Specifications
Synonyms
Chromobox protein homolog 6; CBX6
Gene Name
CBX6
UniProt
O95503
Reactivity
Human, Mouse, Rat
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development (PubMed:21282530) . PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin (PubMed:18927235) . Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity) . May have a PRC1-independent function in embryonic stem cells (By similarity) .
Molecular Weight
43898 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Product Datasheet
https://www.bosterbio.com/datasheet?sku=EKC1662
Product MSDS
https://www.bosterbio.com/msds?sku=EKC1662
Other Gene Names
Chromobox protein homolog 6
Subcellular Location
Nucleus. Chromosome. Uniformely distributed in the nucleoplasm (PubMed:18927235) . Localizes to the inactivated X chromosome in females (By similarity) .
Curated Selection
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