FIR Colorimetric Cell-Based ELISA
The FIR Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor FIR protein expression profile in cells. The kit can be used for measuring the relative amounts of FIR in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on FIR.
Product Specifications
Synonyms
FERM, ARHGEF and pleckstrin domain-containing protein 2; FERM domain-including RhoGEF; FIR; FERM, RhoGEF and pleckstrin domain-containing protein 2; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3; FARP2; KIAA0793, PLEKHC3
Gene Name
FARP2
UniProt
O94887
Reactivity
Human, Mouse
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Functions as guanine nucleotide exchange factor that activates RAC1. May have relatively low activity. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton. Plays a role in TNFSF11-mediated osteoclast differentiation, especially in podosome rearrangement and reorganization of the actin cytoskeleton. Regulates the activation of ITGB3, integrin signaling and cell adhesion (By similarity) .
Molecular Weight
119888 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
FERM, ARHGEF and pleckstrin domain-containing protein 2
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