LAT3 Colorimetric Cell-Based ELISA

The LAT3 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor LAT3 protein expression profile in cells. The kit can be used for measuring the relative amounts of LAT3 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on LAT3.

Product Specifications

Synonyms

Large neutral amino acids transporter small subunit 3; L-type amino acid transporter 3; Prostate cancer overexpressed gene 1 protein; Solute carrier family 43 member 1; SLC43A1 ; LAT3 , PB39 , POV1

Gene Name

SLC43A1 LAT3 , PB39 , POV1

UniProt

O75387

Reactivity

Human

Tissue Specificity

In adults, found in all tissues examined with highest expression in pancreas. In fetus, highest expression in liver and lower levels in kidney, and lung. High levels found in prostate cancer cells.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Sodium-independent, high affinity transport of large neutral amino acids. Has narrower substrate selectivity compared to SLC7A5 and SLC7A8 and mainly transports branched-chain amino acids and phenylalanine. Plays a role in the development of human prostate cancer, from prostatic intraepithelial neoplasia to invasive prostate cancer.