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SDCG1 Colorimetric Cell-Based ELISA

The SDCG1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor SDCG1 protein expression profile in cells. The kit can be used for measuring the relative amounts of SDCG1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on SDCG1.

Product Specifications

Synonyms

Nuclear export mediator factor NEMF; Antigen NY-CO-1; Serologically defined colon cancer antigen 1; NEMF; SDCCAG1

Gene Name

NEMF

UniProt

O60524

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in brain, heart, liver, lung, spleen, and skeletal muscle. Also expressed at lower levels in stomach and testis.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Component of the ribosome quality control complex (RQC), a ribosome-associated complex that mediates ubiquitination and extraction of incompletely synthesized nascent chains for proteasomal degradation. NEMF is responsible for selective recognition of stalled 60S subunits by recognizing an exposed, nascent chain-conjugated tRNA moiety. NEMF is important for the stable association of LTN1 to the complex (PubMed:25578875) . May indirectly play a role in nuclear export (PubMed:16103875) .

Molecular Weight

122954 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Nuclear export mediator factor NEMF

Subcellular Location

Nucleus.

Frequently Asked Questions

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