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M3K13 Colorimetric Cell-Based ELISA

The M3K13 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor M3K13 protein expression profile in cells. The kit can be used for measuring the relative amounts of M3K13 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on M3K13.

Product Specifications

Synonyms

Mitogen-activated protein kinase kinase kinase 13;2.7.11.25; Leucine zipper-bearing kinase; Mixed lineage kinase; MLK; MAP3K13 ; LZK

Gene Name

MAP3K13 LZK

UniProt

O43283

Reactivity

Human, Mouse, Rat

Tissue Specificity

Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Molecular Weight

108296 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

Mitogen-activated protein kinase kinase kinase 13

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein.

Frequently Asked Questions

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