KLF11 Colorimetric Cell-Based ELISA
The KLF11 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor KLF11 protein expression profile in cells. The kit can be used for measuring the relative amounts of KLF11 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on KLF11.
Product Specifications
Synonyms
Krueppel-like factor 11; Transforming growth factor-beta-inducible early growth response protein 2; TGFB-inducible early growth response protein 2; TIEG-2; KLF11; FKLF, TIEG2
Gene Name
KLF11
UniProt
O14901
Reactivity
Human, Mouse
Tissue Specificity
Ubiquitous. Higher expression in erythroid cells.
Applications
ELISA
Detection Range
> 5000 cells/well
Function
Transcription factor (PubMed:9748269, PubMed:10207080) . Activates the epsilon- and gamma-globin gene promoters and, to a much lower degree, the beta-globin gene and represses promoters containing SP1-like binding inhibiting cell growth (PubMed:9748269, PubMed:10207080, PubMed:16131492) . Represses transcription of SMAD7 which enhances TGF-beta signaling (By similarity) . Induces apoptosis (By similarity) .
Molecular Weight
55139 MW
Shipping Conditions
Available
Storage Conditions
Store at 4°C for up to 6 months.
Other Gene Names
Krueppel-like factor 11
Subcellular Location
Nucleus.
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