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PDLIM1 Colorimetric Cell-Based ELISA

The PDLIM1 Cell-Based ELISA Kit is a convenient, lysate-free, high throughput and sensitive assay kit that can monitor PDLIM1 protein expression profile in cells. The kit can be used for measuring the relative amounts of PDLIM1 in cultured cells as well as screening for the effects that various treatments, inhibitors (ie. siRNA or chemicals), or activators have on PDLIM1.

Product Specifications

Synonyms

PDZ and LIM domain protein 1; C-terminal LIM domain protein 1; Elfin; LIM domain protein CLP-36; PDLIM1; CLIM1, CLP36

Gene Name

PDLIM1

UniProt

O00151

Reactivity

Human, Mouse, Rat

Tissue Specificity

Strongly expressed in the heart and skeletal muscle, moderately expressed in the spleen, small intestine, colon, placenta, and lung. A lower level expression is seen in liver, thymus, kidney, prostate and pancreas and is not found in the brain, testis, ovary, and peripheral blood leukocytes.

Applications

ELISA

Detection Range

> 5000 cells/well

Function

Cytoskeletal protein that may act as an adapter that brings other proteins (like kinases) to the cytoskeleton (PubMed:10861853) . Involved in assembly, disassembly and directioning of stress fibers in fibroblasts. Required for the localization of ACTN1 and PALLD to stress fibers. Required for cell migration and in maintaining cell polarity of fibroblasts (By similarity) .

Molecular Weight

36072 MW

Shipping Conditions

Available

Storage Conditions

Store at 4°C for up to 6 months.

Other Gene Names

PDZ and LIM domain protein 1

Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasm, myofibril, sarcomere, Z line. Associates with actin stress fibers.

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